Fluvoxamine-induced erectile dysfunction responding to sildenafil.

Abstract

Sildenafil, a peripherally acting inhibitor of cyclic guanosine monophosphate((cGMP), has been reported highly effective in treating erectile dysfunction of various etiology. Erectile dysfunction is a common sexual side effect of various antidepressants. Various agents have been used in the treatment of antidepressant-induced erectile dysfunction; however, there are no reports on the use of sildenafil for this indication. This case report describes the successful use of sildenafil in fluvoxamine-induced erectile dysfunction. A possible mechanism of action of sildenafil in this type of erectile dysfunction is discussed.

• Authors: R Balon
• Journal: Journal of sex & marital therapy (J Sex Marital Ther) 1998 Oct-Dec Vol. 24 Issue 4 Pg. 313-7 ISSN: 0092-623X [Print] England
• PMID: 9805292 (Publication Type: Case Reports, Journal Article)

Chemical References

• Enzyme Inhibitors
• Piperazines
• Purines
• Serotonin Uptake Inhibitors
• Sulfones
• Sildenafil Citrate
• Fluvoxamine

Topics

• Adult
• Enzyme Inhibitors (therapeutic use)
• Fluvoxamine (adverse effects)
• Humans
• Male
• Penile Erection (drug effects)
• Piperazines (pharmacology, therapeutic use)
• Purines
• Selective Serotonin Reuptake Inhibitors (adverse effects)
• Sexual Dysfunction, Physiological (chemically induced, drug therapy)
• Sildenafil Citrate
• Sulfones