Treatment of mononeuropathy multiplex in hepatitis C virus and cryoglobulinemia.

Abstract

Recent reports advocate alpha-interferon (alpha-Ifn) treatment for mononeuropathy multiplex in hepatitis C virus-associated cryoglobulinemia. We report 2 patients with this disorder to describe two underrecognized treatment outcomes--worsening of polyneuropathy with initiation of alpha-Ifn, in the absence of immunosuppression, and deterioration of liver function with prednisone, despite improvement of polyneuropathy.

• Authors: S N Scelsa, S Herskovitz, B Reichler
• Journal: Muscle & nerve (Muscle Nerve) Vol. 21 Issue 11 Pg. 1526-9 (Nov 1998) ISSN: 0148-639X [Print] United States
• PMID: 9771679 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Antiviral Agents
• Interferon-alpha
• Prednisone

Topics

• Adult
• Anti-Inflammatory Agents (administration & dosage)
• Antiviral Agents (administration & dosage)
• Cryoglobulinemia (therapy, virology)
• Female
• Hepatitis C (complications, therapy)
• Humans
• Interferon-alpha (administration & dosage)
• Male
• Middle Aged
• Motor Neurons (physiology, virology)
• Peripheral Nervous System Diseases (drug therapy, virology)
• Prednisone (administration & dosage)