Precancerous lesions of the endometrium and medical treatment.

Abstract

Endometrial hyperplasias, which occur in the premenopausal age and are often induced by anovulatory cycles, are kept under control by progestin therapy. The good results with natural and synthetic progestins suggest that this treatment can be used both in premenopause and postmenopause hyperplasia. The progestin effect on the endometrium appears through a marked pseudodecidual reaction of the stroma and functional atrophy of the glands. These events are reported in the literature as inactive or suppressed endometrium and there is no physiological equivalent.

• Authors: G L Taddei, G Bargelli, B Scarselli, D Moncini, G Scarselli
• Journal: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception (Eur J Contracept Reprod Health Care) Vol. 2 Issue 4 Pg. 239-41 (Dec 1997) ISSN: 1362-5187 [Print] England
• PMID: 9678079 (Publication Type: Journal Article, Review)

Chemical References

• Progesterone Congeners
• Progestins
• Levonorgestrel

Topics

• Drug Monitoring
• Endometrial Hyperplasia (diagnosis, drug therapy)
• Endometrial Neoplasms (diagnosis, drug therapy)
• Female
• Humans
• Intrauterine Devices, Medicated
• Levonorgestrel
• Postmenopause
• Precancerous Conditions (diagnosis, drug therapy)
• Premenopause
• Progesterone Congeners
• Progestins (pharmacology, therapeutic use)