Radiation-induced malignant mesenchymoma of the chest wall following treatment for breast cancer.

Abstract

21 years after radiotherapy for breast cancer, a 63-year-old woman developed a malignant mesenchymoma of the chest wall. The total irradiation dose was 132 Gy. The first clinical symptom of this second malignancy was a slight irregular calcification around the implanted silicon protheses observed in a conventional chest X-ray. Radiation-induced sarcoma is a very rare complication of radiotherapy. In cases of chest wall calcification after radiation therapy further investigation should be carried out, because some patients with radiation-induced sarcoma could be saved, if an early diagnosis is reached.

• Authors: P Rustemeyer, O Micke, S Blasius, P E Peters
• Journal: The British journal of radiology (Br J Radiol) Vol. 70 Issue 832 Pg. 424-6 (Apr 1997) ISSN: 0007-1285 [Print] England
• PMID: 9166083 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Breast Neoplasms (radiotherapy)
• Female
• Follow-Up Studies
• Humans
• Mesenchymoma (diagnostic imaging, etiology)
• Neoplasms, Radiation-Induced (diagnostic imaging, etiology)
• Neoplasms, Second Primary (diagnostic imaging, etiology)
• Radiography
• Radiotherapy (adverse effects)
• Thoracic Neoplasms (diagnostic imaging, etiology)