[Pathology and clinical aspects of retarded child development. Diagnosis and therapy of defective development].

Abstract

21 cases of "small for date" pregnancies were analysed. Serial ultrasonic tracings and determinations of total estrogen excretion in the 24-hour-urine and of serum HPL concentration were carried out. The fetal heart rate was measured by cardiotocogram. Retrospectively, the patients were divided into 3 groups according to birth weight. All patients were treated with a combination of Complamin, Calciparin and Partusisten. Fetal growth retardation could not be stopped by this treatment; there was, however, definite fetal weight gain following long term therapy. Results of HPL and total estrogen determinations were inconclusive; in most cases, however, a fall of concentrations was observed. Following long term therapy a rise in concentration up to almost normal values was seen. The positive effect of therapy was best shown by serial cardiotograms.

• Authors: H H Senft, H Kugener, W Korte
• Journal: Fortschritte der Medizin (Fortschr Med) Vol. 95 Issue 39 Pg. 2397-402 (Oct 20 1977) ISSN: 0015-8178 [Print] Germany
• Vernacular Title: Pathologie und Klinik der retardierten Kindesentwicklung. Diagnose und Therapie der Mangelentwicklung.
• PMID: 914199 (Publication Type: English Abstract, Journal Article)

Chemical References

• Fenoterol
• Xanthinol Niacinate
• Heparin
• Betamethasone

Topics

• Betamethasone (therapeutic use)
• Birth Weight
• Drug Therapy, Combination
• Female
• Fenoterol (therapeutic use)
• Fetal Growth Retardation (diagnosis, therapy)
• Heparin (therapeutic use)
• Humans
• Infant, Newborn
• Placental Insufficiency (drug therapy)
• Pregnancy
• Ultrasonics
• Uterine Contraction (drug effects)
• Xanthinol Niacinate (therapeutic use)