Technetium-99m glucoheptonate in brain-tumor detection: an important advance in radiotracer techniques.

Abstract

We have compared [Tc-99m] sodium pertechnetate with Tc-99m glucoheptonate in 52 patients studied for various brain lesions. Flow studies as well as delayed scans were performed in all. Especially in primary and metastatic lesions of the posterior fossa, the diagnostic yield was improved by the delayed glucoheptonate (GH) scans. In contrast, no advantage of GH over pertechnetate could be detected in the study of infarcts or other ischemic lesions. Various hypotheses are discussed to explain the observed differences in behavior between the two tracers.

• Authors: J Léveillé, C Pison, Y Karakand, R Lemieux, B J Vallières
• Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine (J Nucl Med) Vol. 18 Issue 10 Pg. 957-61 (Oct 1977) ISSN: 0161-5505 [Print] United States
• PMID: 903478 (Publication Type: Journal Article)

Chemical References

• Heptoses
• Sugar Acids
• Technetium
• alpha-glucoheptonic acid

Topics

• Adult
• Aged
• Brain Neoplasms (diagnostic imaging)
• Female
• Heptoses (metabolism)
• Humans
• Male
• Middle Aged
• Neoplasm Metastasis
• Radionuclide Imaging (methods)
• Sugar Acids (metabolism)
• Technetium