Complete atrioventricular block due to large cell lymphoma: resolution with chemotherapy.

Abstract

Malignant lymphoma commonly involves the heart. Previous studies have found cardiac metastases in up to 20% of patients dying with lymphoma. Cardiac signs and symptoms of lymphoma are relatively rare, however, and in most cases, the diagnosis is made either postmortem or too late to affect the clinical course. This report presents the first case of complete heart block due to lymphoma that responded to surgery and chemotherapy with return of normal atrial ventricular conduction.

• Authors: M C Giudici, R L Sadler, J A Robken, M A Ahearn, R Sekharan, G Kovach
• Journal: Clinical cardiology (Clin Cardiol) Vol. 19 Issue 3 Pg. 262-4 (Mar 1996) ISSN: 0160-9289 [Print] United States
• PMID: 8674270 (Publication Type: Case Reports, Journal Article)

Chemical References

• Vincristine
• Doxorubicin
• Cyclophosphamide
• Prednisone

Topics

• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Atrioventricular Node (physiology)
• Combined Modality Therapy
• Cyclophosphamide (administration & dosage)
• Doxorubicin (administration & dosage)
• Female
• Heart Atria (surgery)
• Heart Block (etiology)
• Heart Neoplasms (complications, drug therapy, surgery)
• Humans
• Lymphoma, Large B-Cell, Diffuse (complications, drug therapy, surgery)
• Middle Aged
• Prednisone (administration & dosage)
• Vincristine (administration & dosage)