Abstract | OBJECTIVE: METHODS: HLA class I antigens and HLA class II alleles were determined in 43 Japanese patients with anti-U1 RNP antibody alone, by microcytotoxicity testing and DNA typing, respectively. Prospectively recorded clinical and laboratory features were analyzed in relation to HLA class I and class II types. RESULTS: CONCLUSION: These HLA-clinical associations explain, in part, the heterogeneous clinical presentation in patients with anti-U1 RNP antibody.
|
Authors | M Kuwana, Y Okano, J Kaburaki, H Inoko |
Journal | Arthritis and rheumatism
(Arthritis Rheum)
Vol. 39
Issue 6
Pg. 938-42
(Jun 1996)
ISSN: 0004-3591 [Print] United States |
PMID | 8651987
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Antibodies
- HLA Antigens
- Ribonucleoprotein, U1 Small Nuclear
|
Topics |
- Adolescent
- Adult
- Alleles
- Antibodies
- Child
- Connective Tissue Diseases
(immunology)
- Female
- Genes, MHC Class I
- Genes, MHC Class II
- HLA Antigens
(genetics)
- Humans
- Japan
- Male
- Middle Aged
- Prospective Studies
- Ribonucleoprotein, U1 Small Nuclear
(immunology)
- Statistics as Topic
|