[Histochemical study of the activity of several enzymes in the process of immunogenesis in monkeys orally infected with viruses of the tick-borne encephalitis complex].

Abstract

The activity of succinate dehydrogenase, acid and alkaline phosphatase was studied histochemically in immunocompetent organs of Macacus rhesus monkeys orally infected with viruses of the tick-borne encephalitis complex with different biological properties. A gradual increase in the activity of acid phosphatase and succinate dehydrogenase was observed by the 10th--15th day of the experiment followed by its decline to normal by 90 days. The content of alkaline phosphatase in lympoid organs diminished markedly in the first day of the study and then increased by 15--30 days after antigenic stimulation.

• Authors: A V Dubov, S P Gladyshev
• Journal: Voprosy virusologii (Vopr Virusol) 1976 May-Jun Issue 3 Pg. 337-41 ISSN: 0507-4088 [Print] Russia (Federation)
• Vernacular Title: Gistokhimicheskoe izuchenie aktivnostinekotorych fermentov v protsesse immunogeneza u obez'ian, peroral'no zarazhennykh virusami kompleksa kleshchevogo éntsefalita
• PMID: 824823 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antibodies, Viral
• Succinate Dehydrogenase
• Alkaline Phosphatase
• Acid Phosphatase

Topics

• Acid Phosphatase (metabolism)
• Alkaline Phosphatase (metabolism)
• Animals
• Antibodies, Viral (biosynthesis)
• Encephalitis, Tick-Borne (enzymology, immunology)
• Haplorhini
• Histocytochemistry
• Kupffer Cells (enzymology)
• Lymph Nodes (enzymology)
• Lymphoid Tissue (enzymology, immunology)
• Macaca mulatta
• Macrophages (enzymology)
• Spleen (enzymology)
• Succinate Dehydrogenase (metabolism)
• Thymus Gland (enzymology)