[The efficacy of verapamil in sustained monomorphic ventricular tachycardia].

Abstract

We present a 36-year-old male without overt cardiac disease who suffered, since he was 15 years old, from sustained monomorphic ventricular tachycardia of left bundle branch block with a right axis, lasting for several hours; sometimes, syncope was a clinical form of manifestation. Electrophysiologic study, twenty-four hours Holter recording, cardiac catheterization and blood analysis were not useful in order to find its etiology. Efficacy of different drugs, like Mexiletil, Amiodarone, Atenolol and Verapamil (at a dose of 240 mg/day) were tested through multistaged graded-treadmill stress-testing using the Bruce protocol. Ventricular tachycardia was suppressed by administration of Lidocaine. Oral verapamil given at a dose of 360 mg/day prevented the induction of the arrhythmia, the efficacy was tested with maximal treadmill exercise and twenty-four hours Holter recording.

• Authors: J R Rumoroso, A Bodegas, J Subinas, P M Montes, R Sanz, D Rodrigo, J I Barrenetxea
• Journal: Revista espanola de cardiologia (Rev Esp Cardiol) Vol. 47 Issue 9 Pg. 633-5 (Sep 1994) ISSN: 0300-8932 [Print] Spain
• Vernacular Title: Eficacia del verapamilo en la taquicardia ventricular monomorfa sostenida.
• PMID: 7973032 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Verapamil

Topics

• Adult
• Cardiac Pacing, Artificial
• Chronic Disease
• Drug Evaluation
• Electrocardiography, Ambulatory (drug effects)
• Exercise Test (drug effects)
• Humans
• Male
• Tachycardia, Ventricular (diagnosis, drug therapy)
• Verapamil (therapeutic use)