Abstract |
The aim of this study was to determine the MR imaging features of hepatic metastases from pancreatic neuroendocrine tumors (HMPNT), and to assess their enhancement characteristics on dynamic gadolinium-chelate-enhanced MR imaging. Twelve consecutive patients with pathologically proven HMPNT underwent spin-echo (SE) and dynamic gradient-recalled echo (GRE) MR imaging before and after intravenous administration of a gadolinium-chelate ( gadolinium tetraazacyclododecanetetraacetic acid; Gd-DOTA). MR examinations were performed prospectively and interpreted retrospectively in consensus by two radiologists. Fifty-five HMPNT were identified in matching anatomic sections on the different MR sequences and included in the study. On T1-weighted SE images, 45 HMPNT (82%) were hypointense and 10 HMPNT (18%) were isointense. On T2-weighted SE images 55 HMPNT (100%) were hyperintense. On GRE images obtained 20 s after Gd-DOTA injection, 41 HMPNT (75%) showed slight peripheral enhancement, and 14 HMPNT (25%) showed internal enhancement. Forty-four HMPNT (80%) were heterogeneous. On GRE images obtained 4 min after Gd-DOTA injection, 37 HMPNT (67%) showed peripheral enhancement, and 18 HMPNT (33%) showed a global and almost complete enhancement. Heterogeneity of enhancement was seen in all 55 HMPNT (100%). Although HMPNT exhibit a large spectrum of MR features, early enhancement and heterogeneity on dynamic GRE MR images are suggestive features of HMPNT.
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Authors | P Soyer, K Tidjani, J P Laissy, A Sibert, Y Menu |
Journal | European journal of radiology
(Eur J Radiol)
Vol. 18
Issue 3
Pg. 180-4
(Aug 1994)
ISSN: 0720-048X [Print] Ireland |
PMID | 7957287
(Publication Type: Journal Article)
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Chemical References |
- Chelating Agents
- Contrast Media
- Heterocyclic Compounds
- Organometallic Compounds
- gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate
- Gadolinium
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Topics |
- Adult
- Aged
- Carcinoid Tumor
(pathology, secondary)
- Chelating Agents
(administration & dosage)
- Contrast Media
(administration & dosage)
- Female
- Gadolinium
(administration & dosage)
- Gastrinoma
(pathology, secondary)
- Heterocyclic Compounds
(administration & dosage)
- Humans
- Image Enhancement
(methods)
- Insulinoma
(pathology, secondary)
- Liver Neoplasms
(diagnosis, pathology, secondary)
- Magnetic Resonance Imaging
(methods)
- Male
- Middle Aged
- Neuroendocrine Tumors
(diagnosis, pathology, secondary)
- Organometallic Compounds
(administration & dosage)
- Pancreatic Neoplasms
(pathology)
- Prospective Studies
- Retrospective Studies
- Vipoma
(pathology, secondary)
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