[Efficacy of the combination of 5 fluorouracil, adriamycin and cisplatin (FAP protocol) in the treatment of metastatic cylindroma. Apropos of a case with review of the literature].

Abstract

We report the case of a 43 year-old woman who was submitted to a complete surgical resection of an Adenoid Cystic Carcinoma (ACC) of the submandibular salivary gland which was associated with diffuse lung metastases. Combination chemotherapy with fluoro-5-uracil, adriamycin, and cisplatin (FAP) induced an almost complete disappearance of the chest lesions. The literature about ACC and its chemotherapy is reviewed.

• Authors: F Farhat, J Kattan, S Culine, M Bekradda, J P Droz
• Journal: Bulletin du cancer (Bull Cancer) Vol. 81 Issue 1 Pg. 47-50 (Jan 1994) ISSN: 0007-4551 [Print] France
• Vernacular Title: Efficacité de l'association 5-fluorouracile, adriamycine et cisplatinum (FAP) dans le traitement des cylindromes métastatiques. A propos d'un cas avec revue de la littérature.
• PMID: 7949584 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Doxorubicin
• Cisplatin
• Fluorouracil

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Carcinoma, Adenoid Cystic (drug therapy, secondary)
• Cisplatin (administration & dosage)
• Dose-Response Relationship, Drug
• Doxorubicin (administration & dosage)
• Female
• Fluorouracil (administration & dosage)
• Humans
• Lung Neoplasms (drug therapy, secondary)
• Submandibular Gland Neoplasms (therapy)