[Nitrogen oxide inhalation in acute pulmonary failure].

Abstract

Two cases of adult respiratory distress syndrome (ARDS) treated successfully with nitric oxide (NO) inhalation are described. One patient had severe sepsis and the other had trauma induced ARDS. The slow entry criteria for extracorporeal membrane oxygenation (ECMO) was fulfilled in both cases. NO inhalation substantially improved oxygenation, reduced pulmonary arterial pressure and peak inspiratory pressure. Treatment with NO inhalation was without side effects and easy to administer through the ventilator. Both patients survived without sequelae. We suggest that inhalation with NO should be tried before ECMO treatment is considered in severe ARDS.

• Authors: T H Jensen, S W Henneberg, L Heslet, P K Andersen
• Journal: Ugeskrift for laeger (Ugeskr Laeger) Vol. 157 Issue 20 Pg. 2862-4 (May 15 1995) ISSN: 0041-5782 [Print] Denmark
• Vernacular Title: Nitrogenoxidinhalation ved akut lungesvigt.
• PMID: 7785104 (Publication Type: Case Reports, Journal Article)

Chemical References

• Nitric Oxide

Topics

• Adolescent
• Adult
• Extracorporeal Membrane Oxygenation
• Female
• Humans
• Male
• Nitric Oxide (administration & dosage)
• Respiratory Distress Syndrome (therapy)
• Treatment Outcome