[Use of inhalation anesthetics in treatment of severe status asthmaticus and for anesthesia in children suffering from bronchial asthma. Preliminary report].

Abstract

This paper presents preliminary estimation of clinical usefulness of isoflurane for treatment of severe cases of status asthmaticus in children and application of it as monoanesthesia in children with bronchial asthma, operated upon sudden indications. Action and metabolism of halogen ether group inhalatory anaesthetics in human organism was discussed, with special attention being paid to isoflurane and ketamine. In the cases studied (which is also confirmed by numerous clinical tests) potentialization of bronchodilatative effect of isoflurane by intravenous application of ketamine in status asthmaticus was observed. Where the results achieved was linked up with increased concentration of catecholamines and direct atonic effect on smooth muscular coat of bronchus.

• Authors: M Sada-Cieślar, G Bujok, M Kudła
• Journal: Pneumonologia i alergologia polska (Pneumonol Alergol Pol) Vol. 63 Issue 3-4 Pg. 209-14 ( 1995) ISSN: 0867-7077 [Print] Poland
• Vernacular Title: Zastosowanie wziewnych środków anestetycznych w leczeniu ciezkich stanów astmatycznych oraz w znieczuleniu u dzieci chorych na astme oskrzelowa. Doniesienie wstepne.
• PMID: 7647737 (Publication Type: English Abstract, Journal Article)

Chemical References

• Ketamine
• Isoflurane

Topics

• Administration, Inhalation
• Adolescent
• Anesthesia, Inhalation
• Asthma (surgery)
• Bronchi (drug effects)
• Child
• Child, Preschool
• Humans
• Infant
• Injections, Intravenous
• Isoflurane (pharmacology, therapeutic use)
• Ketamine (pharmacology, therapeutic use)
• Muscle, Smooth (drug effects)
• Status Asthmaticus (drug therapy)