[The determination of neurospecific proteins in the blood of patients with closed craniocerebral trauma and their diagnostic significance].

Abstract

Data are reported on the content of neurospecific proteins in the blood serum of 87 patients with closed head injuries. It has been established that the method of competent EIA can be used for measuring the content of neurospecific proteins. It has also been shown that their content in the blood depended on the severity of injury: the more severe injury the higher the protein content. Some aspects have been revealed of the blood content of protein 14-3-2 and total myelin protein. The authors discuss a possible diagnostic importance of these proteins in the differential diagnosis of the severity of closed head injuries and in the determination of lesions of the neuroglia and neurons both in mild and grave trauma.

• Authors: I I Lisianyĭ, T M Cheren'ko, S V Komissarenko, G A Berezhnoĭ, N Kh Tukhtiev, R S Arustamian
• Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (Zh Nevrol Psikhiatr Im S S Korsakova) Vol. 93 Issue 2 Pg. 50-3 ( 1993) ISSN: 1997-7298 [Print] Russia (Federation)
• Vernacular Title: Opredelenie neĭrospetsificheskikh belkov v krovi bol'nykh s zakrytoĭ cherepno-mozgovoĭ travmoĭ i ikh diagnosticheskoe znachenie.
• PMID: 7519386 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Biomarkers
• Myelin Basic Protein
• Nerve Tissue Proteins

Topics

• Biomarkers (blood)
• Brain Concussion (blood, diagnosis)
• Head Injuries, Closed (blood, diagnosis)
• Humans
• Immunoenzyme Techniques
• Myelin Basic Protein (blood)
• Nerve Tissue Proteins (blood)
• Oligodendroglia (metabolism)
• Time Factors