Stability of remission during tricyclic antidepressant continuation therapy for dysthymia.

Abstract

Sixty-four of 73 patients with DSM-III-R dysthymia who responded to short-term treatment with tricyclic antidepressants (TCAs) completed 16 to 20 weeks of continuation therapy on the same medication. Forty-one of 46 full remitters remained in full remission, while 5 became partial remitters during the continuation treatment. Of 18 partial remitters, 8 became fully remitted, 8 remained partial remitters, and 2 relapsed. Thus the stability of remission in dysthymic subjects treated with TCA seems quite favorable during continuation treatment.

• Authors: J H Kocsis, R A Friedman, J C Markowitz, N Miller, L Gniwesch, J Bram
• Journal: Psychopharmacology bulletin (Psychopharmacol Bull) Vol. 31 Issue 2 Pg. 213-6 ( 1995) ISSN: 0048-5764 [Print] United States
• PMID: 7491370 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Antidepressive Agents, Tricyclic

Topics

• Adult
• Antidepressive Agents, Tricyclic (therapeutic use)
• Depression (drug therapy)
• Depressive Disorder (drug therapy)
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Time Factors
• Treatment Outcome