Gm allotypes and multiple sclerosis.

Abstract

Immunoglobulin allotypes (Gm) were analysed in 40 multiple sclerosis (MS) patients and the distribution of phenotypes compared to that in 1220 healthy controls. The frequencies of GM(1) and Gm(1, 2) are significantly increased inthe patients suggesting that the presence of the Gm3;5, 13, 14 haplotype confers a resistance to the development of MS.

• Authors: D N Propert, C C Bernard, M J Simons
• Journal: Journal of immunogenetics (J Immunogenet) Vol. 9 Issue 5 Pg. 359-61 (Oct 1982) ISSN: 0305-1811 [Print] England
• PMID: 7175205 (Publication Type: Journal Article)

Chemical References

• Immunoglobulin Allotypes

Topics

• Female
• Humans
• Immunoglobulin Allotypes (genetics)
• Male
• Multiple Sclerosis (genetics, immunology)