Abstract |
The antiepileptic properties of carbamazepine ( Tegretol) and clonazepam ( Rivotril) were compared in a double-blind randomized study comprising 36 patients with newly diagnosed, untreated psychomotor epilepsy ( partial seizures with complex symptomatology). No significant differences were found between the two drugs during the 6 months of treatment. Measurements of concentrations in plasma confirmed that the patients exceeded the accepted lower limit for therapeutic range of the drugs.
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Authors | B Mikkelsen, P Berggreen, P Joensen, O Kristensen, O Køhler, B O Mikkelsen |
Journal | Epilepsia
(Epilepsia)
Vol. 22
Issue 4
Pg. 415-20
(Aug 1981)
ISSN: 0013-9580 [Print] United States |
PMID | 7021140
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Benzodiazepinones
- Carbamazepine
- Clonazepam
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Topics |
- Adolescent
- Adult
- Aged
- Benzodiazepinones
(therapeutic use)
- Carbamazepine
(administration & dosage, therapeutic use)
- Child
- Clinical Trials as Topic
- Clonazepam
(administration & dosage, therapeutic use)
- Double-Blind Method
- Epilepsy, Temporal Lobe
(drug therapy)
- Female
- Humans
- Male
- Middle Aged
- Random Allocation
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