[Continuous perfusion of low doses of insulin in severe diabetic decompensation (author's transl)].

Abstract

Twenty one episodes of severe uncontrolled diabetes, most of them with ketoacidosis, were treated at a Medical Intensive Care Unit with fluid and electrolyte replacement and continuous perfusion of low doses of insulin. The overall results of this therapeutic approach were a progressive and gradual return to normality of all biochemical parameters with a fall of serum glucose levels and no hypoglycemic or hypokalemic accidents. Based on this study and on a review of the literature, an updated protocol for therapy of diabetic ketoacidosis is proposed.

• Authors: M Herrera Carranza, J Rubio Quiñones, J J Pou Dimaio, J Leal del Ojo González, J C Medina Sierra, M Tejedor Fernández, J M Garcĩa Castilla
• Journal: Medicina clinica (Med Clin (Barc)) Vol. 76 Issue 3 Pg. 117-20 (Feb 10 1981) ISSN: 0025-7753 [Print] Spain
• Vernacular Title: Perfusión contunua de bajas dosis de insulina en la descompensación diabética grave.
• PMID: 6782392 (Publication Type: English Abstract, Journal Article)

Chemical References

• Blood Glucose
• Insulin
• Potassium

Topics

• Adolescent
• Adult
• Aged
• Blood Glucose
• Child
• Diabetes Mellitus (drug therapy)
• Diabetic Ketoacidosis (drug therapy)
• Female
• Humans
• Hydrogen-Ion Concentration
• Hyperglycemic Hyperosmolar Nonketotic Coma (drug therapy)
• Insulin (administration & dosage)
• Male
• Middle Aged
• Potassium (blood)