Abstract |
Normal rats were injected with a smooth-muscle activating factor (SMAF) to examine the dose-response relationshio of SMAF to the incidence of decompression sickness. After injections of saline or 1.0, 5.0, or 10.0 mg/kg SMAF, the animals were compressed to 6 ATA breathing air for 1 h and were then rapidly decompressed to 1 ATA. Results indicate that predive injections of SMAF or exposure to the SMAF substance protected rats against decompression sickness and that higher doses appear to offer more protection.
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Authors | J M Walsh, J Vorosmarti Jr |
Journal | Undersea biomedical research
(Undersea Biomed Res)
Vol. 5
Issue 2
Pg. 129-35
(Jun 1978)
ISSN: 0093-5387 [Print] United States |
PMID | 675878
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Decompression Sickness
(prevention & control)
- Female
- Muscle, Smooth
- Peptides
(pharmacology)
- Rats
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