Abstract |
O-(beta-hydroxyethyl)- rutoside (HR) ( Venoruton, Zyma AS, Nyon, Switzerland) has been investigated experimentally to evaluate the effect on microvascular permeability and thromboembolism. Permeability to macromolecules is diminished in a hamster cheek-pouch model. Haemostatic plug formation is impaired whereas laser-induced intravascular platelet aggregation is uninfluenced. There is a small but insignificant protection against sodium morrhuate (Eli Lilly and Co., Indianapolis, Indiana) induced femoral vein thrombosis.
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Authors | D Bergqvist, E Svensjö, K E Arfors |
Journal | Upsala journal of medical sciences
(Ups J Med Sci)
Vol. 83
Issue 2
Pg. 123-7
( 1978)
ISSN: 0300-9734 [Print] Sweden |
PMID | 664118
(Publication Type: Journal Article)
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Chemical References |
- Hydroxyethylrutoside
- Macromolecular Substances
- Rutin
- Sodium Morrhuate
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Topics |
- Animals
- Capillary Permeability
(drug effects)
- Cricetinae
- Hemostasis
(drug effects)
- Hydroxyethylrutoside
(blood, pharmacology, therapeutic use)
- Macromolecular Substances
- Male
- Microcirculation
(drug effects)
- Rutin
(analogs & derivatives)
- Sodium Morrhuate
- Thrombophlebitis
(chemically induced, prevention & control)
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