[Assessment of the results of serum enzyme studies in different forms of myocardial infarction].

Abstract

An examination of 400 coronary patients demonstrated a relationship between increased serum CPK, AST, LDH and LDH-1, and the spread and severity of myocardial infarction (MI). In transmural and large-focal MI, CPK activity peak observed on Day 1-2 of the disease was increased 4-12-fold, and that of AST, 5-fold, as compared to the upper limit of the normal range. In small-focal and subendocardial MIs, the increase was 1.5-8-fold and 3-fold, respectively. In angina pectoris, serum CPK activity also showed an increase, although a less manifest one. A CPK activity level of 175 IU is proposed as a discriminative level to be used in the diagnosis of large-focal myocardial infarctions.

• Authors: Z B Tokarskaia, N D Okladnikova, A G Surina
• Journal: Kardiologiia (Kardiologiia) Vol. 23 Issue 7 Pg. 64-9 (Jul 1983) ISSN: 0022-9040 [Print] Russia (Federation)
• Vernacular Title: Otsenka rezul'tatov issledovaniia fermentov syvorotki krovi pri razlichnykh formakh infarkta miokarda.
• PMID: 6620815 (Publication Type: English Abstract, Journal Article)

Chemical References

• Isoenzymes
• L-Lactate Dehydrogenase
• Aspartate Aminotransferases
• Creatine Kinase

Topics

• Adult
• Aged
• Aspartate Aminotransferases (blood)
• Creatine Kinase (blood)
• Female
• Humans
• Isoenzymes
• L-Lactate Dehydrogenase (blood)
• Male
• Middle Aged
• Myocardial Infarction (enzymology)
• Prognosis
• Time Factors