Phospholipids associated with human parotid gland sialoliths.

Abstract

Ca-acidic phospholipid-phosphate complexes (CPLX) were isolated from 6 whole and 2 pooled human parotid sialoliths containing the mineral phases hydroxyapatite, whitlockite and octacalcium phosphate (ash 78 +/- 16 per cent, n = 7). Total lipids accounted for 25 per cent of the demineralized dry weight of these sialoliths. CPLX was 39 +/- 18 per cent of the lipid phosphorous pool, while diphosphatidyl glycerol, phosphatidyl ethanolamine and phosphatidyl choline were the principal non-complexed phospholipids. The high cholesterol:phospholipid molar ratio (1.0 +/- 0.3) observed in the sialolith lipids suggests a plasma membrane origin for these lipids.

• Authors: A L Boskey, L S Burstein, I D Mandel
• Journal: Archives of oral biology (Arch Oral Biol) Vol. 28 Issue 7 Pg. 655-7 ( 1983) ISSN: 0003-9969 [Print] England
• PMID: 6579898 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Lipids
• Minerals
• Phospholipids

Topics

• Humans
• Lipids (analysis)
• Minerals (analysis)
• Parotid Gland (analysis)
• Phospholipids (analysis)
• Salivary Duct Calculi (metabolism)