[The use of a sedative neuroleptic agent, sultopride, in posttraumatic Korsakoff syndrome in a young adult].

Abstract

In a young woman with a post-traumatic Korsakoff syndrome exhibiting agitation and anxiety, sedative drugs were difficult to use as they either exacerbated confusion or generated ataxia. Administration of meprobamate with oral sultopride in a high dosage (2 g per day) was promptly followed by an improvement in the patient's condition. Doses were therefore rapidly tapered (over approximately a month and a half). Complete recovery, which is the well-known outcome, thus took place in favorable conditions, as anxiety and agitation no longer hindered the patient's relationships with others.

• Authors: P Cornier
• Journal: La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris (Sem Hop) Vol. 59 Issue 20 Pg. 1556-7 (May 19 1983) France
• Vernacular Title: Utilisation d'un neuroleptique sédatif, le sultopride, dans le cadre d'un syndrome de korsakoff post-traumatique chez un adulte jeune.
• PMID: 6308781 (Publication Type: Case Reports, Journal Article)

Chemical References

• Psychotropic Drugs
• Sulpiride
• Amisulpride
• Meprobamate

Topics

• Adult
• Amisulpride
• Craniocerebral Trauma (complications)
• Drug Therapy, Combination
• Female
• Humans
• Meprobamate (administration & dosage)
• Neurocognitive Disorders (drug therapy, etiology)
• Psychotropic Drugs (administration & dosage)
• Sulpiride (administration & dosage, analogs & derivatives)