New data do not suggest linkage between the Xg blood group and bipolar illness.

Abstract	The Xg blood group antigen (a genetic marker of a region of the X chromosome at a considerable distance from protan/deutan color blindness) was studied for linkage to bipolar manic-depressive illness. A multigenerational analytic method, taking variable penetrance into account, was used. In our series of six informative pedigrees, very close linkage could be definitively ruled out, and the likelihood of less tight linkage was consistently less than the likelihood of nonlinkage.
Authors	J F Leckman, E S Gershon, M H McGinniss, S D Targum, E D Dibble
Journal	Archives of general psychiatry (Arch Gen Psychiatry) Vol. 36 Issue 13 Pg. 1435-41 (Dec 1979) ISSN: 0003-990X [Print] United States
PMID	518244 (Publication Type: Journal Article)
Chemical References	Blood Group Antigens
Topics	Bipolar Disorder (genetics) Blood Group Antigens Cyclothymic Disorder (genetics) Female Genetic Carrier Screening Genetic Linkage Humans Male Pedigree Phenotype

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