HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

In-vitro synthesis of an anti-BI cold agglutinin complicating a case of lymphoma.

Abstract
A woman of 47 with lymphocytic lymphoma was found to have a high-titer cold autoagglutinin of anit-BI specificity. Her group B erythrocytes autoagglutinated of anti-BI specificity. Her group B erythrocytes autoagglutinated in vitro and the direct antiglobulin reaction was positive, but she had no symptom of cold intolerance, no evidence of hemolysis, and she could receive transfusions of compatible group O erythrocytes. In addition, evidence for synthesis of the autoantibody by the lymphoma cells was obtained by short-term bone-marrow culture.
AuthorsA J Dodds, D Klarkowski, D A Cooper, J P Isbister
JournalAmerican journal of clinical pathology (Am J Clin Pathol) Vol. 71 Issue 4 Pg. 473-5 (Apr 1979) ISSN: 0002-9173 [Print] England
PMID443208 (Publication Type: Case Reports, Journal Article)
Chemical References
  • ABO Blood-Group System
  • Agglutinins
  • Autoantibodies
Topics
  • ABO Blood-Group System
  • Agglutinins (biosynthesis)
  • Autoantibodies (biosynthesis)
  • Bone Marrow Cells
  • Cells, Cultured
  • Cold Temperature
  • Female
  • Humans
  • Lymphoma (immunology)
  • Middle Aged

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: