Normal myelination of regenerating peripheral nerve sprouts despite circulating antibodies to galactocerebroside in rabbits.

Abstract

Rabbits were immunized with galactocerebroside and a crush lesion was created in the tibial nerve before the onset of experimental allergic neuritis. Normal regeneration and myelination of distal peripheral nerve sprouts occurred and was identical to that of controls, although circulating antigalactocerebroside antibodies were present and nerve roots showed typical signs of beginning experimental allergic neuritis.

• Authors: G Stoll, K Reiners, G Schwendemann, K Heininger, K V Toyka
• Journal: Annals of neurology (Ann Neurol) Vol. 19 Issue 2 Pg. 189-92 (Feb 1986) ISSN: 0364-5134 [Print] United States
• PMID: 3963761 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Cerebrosides
• Galactosylceramides
• galactocerebroside

Topics

• Animals
• Cerebrosides (immunology)
• Galactosylceramides (immunology)
• Myelin Sheath (physiology)
• Nerve Regeneration
• Neuritis, Autoimmune, Experimental (physiopathology)
• Peripheral Nerve Injuries
• Rabbits