Prototype of a new protamine sulphate titration kit for use in cardiopulmonary bypass surgery.

Abstract

A new protamine sulphate titration kit has been developed and tested in patients undergoing cardiac bypass surgery. When a prototype of the kit was used, protamine sulphate dosage was significantly reduced (P less than 0.01) without a significant increase in 24-hour postoperative blood loss (P greater than 0.05).

• Authors: E A Shipton, T E Scanes, J N Fiessinger
• Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde (S Afr Med J) Vol. 70 Issue 13 Pg. 809-11 (Dec 20 1986) ISSN: 0256-9574 [Print] South Africa
• PMID: 3798268 (Publication Type: Journal Article)

Chemical References

• Heparin Antagonists
• Protamines
• Reagent Kits, Diagnostic

Topics

• Adult
• Cardiopulmonary Bypass
• Evaluation Studies as Topic
• Heparin Antagonists (analysis, therapeutic use)
• Humans
• Protamines (analysis, therapeutic use)
• Random Allocation
• Reagent Kits, Diagnostic (standards)