Abstract | BACKGROUND AND PURPOSE: METHODS: Embase, Medline, PsychINFO, Cochrane CENTRAL, NGLC, National Institute for Health and Care Excellence Evidence and medRxiv.org were searched for studies with terms relating to population ( Parkinson's disease) and intervention ( rivastigmine). Of 1922 references identified, 358 were duplications. Following title and abstract review, 1331 articles were excluded. After full-text review, nine articles remained. RESULTS: Outcomes were heterogenous, therefore, the results are presented in narrative form. The articles included six randomized controlled trials, two open-label trials and one case series. Outcome measures included: time to develop psychosis; frequency of rapid eye movement sleep behaviour disorder (RBD) episodes; apathy; gait variability; falls; cognitive ability; Neuropsychiatric Inventory score; and regional spontaneous brain activity. CONCLUSIONS:
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Authors | Siobhan Reilly, Simran Dhaliwal, Usman Arshad, Antonella Macerollo, Nusrat Husain, Antonio Da Costa |
Journal | European journal of neurology
(Eur J Neurol)
(Nov 17 2023)
ISSN: 1468-1331 [Electronic] England |
PMID | 37975761
(Publication Type: Journal Article, Review)
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Copyright | © 2023 The Authors. European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology. |