Abstract | OBJECTIVES: METHOD: Six electronic databases (PubMed, SCOPUS, Web of Science, EBSCO, Cochrane, Clinical Trial Registry) were searched to collect studies comparing the effect of probiotics with antibiotics for periodontal disease. In total, 5530 articles were retrieved from all databases, of which 1891 were included for title and abstract screening. After screening, a total of ten clinical studies were included for data extraction and analysis. Probing pocket depth ( PPD), Clinical attachment loss (CAL), bleeding on probing (BOP), plaque index (PI), gingival index (GI), and microbial profile were recorded. RESULTS: Probiotics showed a significant reduction in the PPD and CAL compared to antibiotics. Antibiotics were more effective in reducing the PI and GI. A combination of probiotics and antibiotics superior compared to probiotics and antibiotics alone. CONCLUSION:
|
Authors | Lakshmi Puzhankara, Avishikta Banerjee, Aditi Chopra, Ramanarayanan Venkitachalam, Madhurya N Kedlaya |
Journal | Oral diseases
(Oral Dis)
(Nov 14 2023)
ISSN: 1601-0825 [Electronic] Denmark |
PMID | 37964394
(Publication Type: Journal Article, Review)
|
Copyright | © 2023 The Authors. Oral Diseases published by Wiley Periodicals LLC. |