Abstract | BACKGROUND:
Hypoglycemia is an adverse event (AE) that cannot be ignored in clinical practice. This study aimed to identify the most common and top drugs associated with the risk of hypoglycemia based on the United States Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database. RESEARCH DESIGN AND METHODS: We used OpenVigil 2.1 pharmacovigilance analytics platform to query FAERS database and data from 2004 to 2023 were retrieved. The Medical Dictionary for Regulatory Activities (MedDRA) was used to identify hypoglycemia cases, and DrugBank database was used to determine drug generic names. RESULTS: CONCLUSIONS: By analyzing the FAERS database, we listed drugs with a strong hypoglycemic signal for which the label does not provide a reminder. Notably, the potential hypoglycemia risks are of great importance and should be closely monitored in medical practice.
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Authors | Jie Li, Yilei Wang, Xiang Yang, Haohao Zhu, Zhitao Jiang |
Journal | Expert opinion on drug safety
(Expert Opin Drug Saf)
Pg. 1-7
(Nov 01 2023)
ISSN: 1744-764X [Electronic] England |
PMID | 37909653
(Publication Type: Journal Article)
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