Fractional laser combined with 5-Aminolevulinic acid photodynamic therapy for the treatment of Cutaneous Rosai-Dorfman Disease: A case report.

Abstract

Rosai-Dorfman disease(RDD) is a rare benign histiocytic proliferative disorder. Cutaneous Rosai-Dorfman disease(CRDD)is a rare variant of RDD with lesions localized to the skin. We report a case of patients with CRDD who was refractory to methotrexate, thalidomide, cyclosporine, glucocorticoid for local injection and external use, but resolved with fractional laser combined with 5-aminolevulinic acid photodynamic therapy (ALA-PDT). We believe that fractional laser technology combined with ALA-PDT for CRDD is a minimally invasive, effective and satisfactory treatment.

• Authors: Huan Wang, Chunyou Wang, Xin Wang, Lian Zhang, Min Zhang, Lan Ge, Yi You
• Journal: Photodiagnosis and photodynamic therapy (Photodiagnosis Photodyn Ther) Vol. 44 Pg. 103852 (Oct 18 2023) ISSN: 1873-1597 [Electronic] Netherlands
• PMID: 37858909 (Publication Type: Case Reports)
• Copyright: Copyright © 2023 Elsevier B.V. All rights reserved.