Retrospective comparative study of robot-assisted surgery, laparoscopic surgery, and laparotomy for endometrial cancer in patients with a low risk of recurrence.

Abstract

AIM:

Minimally invasive surgeries for endometrial cancer are increasing worldwide. In Japan, some articles have examined surgical outcomes, but only a few have addressed oncological outcomes. This study aims to compare robot surgery, laparoscopic surgery, and laparotomy in terms of surgical and oncological outcomes within a low-risk group for endometrial cancer recurrence.

METHODS:

This study included patients with endometrial cancer deemed to be at low risk of recurrence and who underwent surgery between January 2011 and December 2020. We studied 99 patients who underwent robot surgery, 85 patients who underwent laparotomy, and 77 patients who underwent laparoscopic surgery. Surgical and oncological outcomes were compared retrospectively for these groups of patients.

RESULTS:

The median follow-up period was 47, 61, and 60 months in the laparotomy, laparoscopy, and robotic groups, respectively. The three groups had similar perioperative and pathological data. No significant differences in overall survival and disease-free survival were observed among the groups. Univariate and multivariate analyses conducted on the overall study population for disease-free survival and overall survival showed that the surgical approach did not have any influence. Minimally invasive surgery groups had longer operating times compared to the laparotomy group, but they had significantly less blood loss. The number of resected pelvic lymph nodes was similar, and the complication rate was not significant.

CONCLUSIONS:

Robot-assisted surgery and laparoscopic surgery were found to be less invasive and showed similar oncologic outcomes compared to laparotomy surgery for endometrial cancer in patients with a low risk of recurrence.

• Authors: Shigehiro Hayashi, Zenta Yamanaka, Junya Kojima, Masataka Ono, Toru Sasaki, Akiko Yamamoto, Masanori Ono, Masayuki Futagami, Hirotaka Nishi
• Journal: The journal of obstetrics and gynaecology research (J Obstet Gynaecol Res) Vol. 50 Issue 1 Pg. 103-112 (Jan 2024) ISSN: 1447-0756 [Electronic] Australia
• PMID: 37848280 (Publication Type: Comparative Study, Journal Article)
• Copyright: © 2023 Japan Society of Obstetrics and Gynecology.

Topics

• Female
• Humans
• Endometrial Neoplasms (pathology, surgery)
• Hysterectomy
• Laparoscopy (adverse effects)
• Laparotomy (adverse effects)
• Neoplasm Recurrence, Local (pathology)
• Neoplasm Staging
• Postoperative Complications (epidemiology)
• Retrospective Studies
• Robotic Surgical Procedures (adverse effects)