Oxidized cellulose-based reaction mimicking thyroidal recurrence of disease: a case report and literature review.

Abstract

Oxidized cellulose is a hemostatic agent currently used in surgery. Foreign body reactions have been described after its use. This paper describes a foreign body reaction caused by oxidized cellulose in a young woman who underwent thyroid surgery. A patient underwent two thyroid surgeries for treatment of papillary carcinoma. Five years after the last surgery, an asymptomatic mass was detected with a routine ultrasound in the left thyroid cavity. After surgical removal, the mass turned out to be a foreign body granuloma based on oxidized cellulose sheets used in the previous surgery. The patient was discharged from the hospital without complications. The follow-up period was uneventful. Oxidized cellulose is a useful tool in surgery to control and prevent intra and post-operative bleeding. Even if it is a biodegradable material, sometimes it persists in the human body causing foreign body reactions that can be misdiagnosed.

Supplementary Information:

The online version contains supplementary material available at 10.1007/s12070-023-03556-0.

• Authors: Carlotta Liberale, Erika Segato, Andrea Sacchetto, Marina Silvestrini, Roberto Saetti
• Journal: Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India (Indian J Otolaryngol Head Neck Surg) Vol. 75 Issue 3 Pg. 2427-2431 (Sep 2023) ISSN: 2231-3796 [Print] India
• PMID: 37636794 (Publication Type: Journal Article)
• Copyright: © The Author(s) 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.