Successful Recovery from Severe Alcoholic Hepatitis (SAH) for Third Time.

Abstract

Alcoholic hepatitis is a clinical syndrome with or without pre-existing chronic liver disease (CLD), and the majority of patients present with acute-on-chronic liver failure (ACLF) having a high 28-day mortality. The treatment of alcoholic hepatitis is suboptimal with corticosteroid having one 1month survival benefit but not translated to a survival benefit beyond six months. Survival benefit has been observed in only about 50-60% of treated patients. Long-term survival depends on underlying liver function and abstinence from alcohol. Relapse is reported in nearly half of the patients who recover from alcoholic hepatitis and even up to 17% after liver transplant. The data on repeated episodes of severe alcoholic hepatitis due to relapse and response to therapy are largely unknown. Here, we report a case of alcoholic hepatitis on three occasions in a period of 2 years follow-up and each time treated with steroids and had complete clinical recovery.

• Authors: Golamari S Reddy, Satender P Singh, S M Shasthry
• Journal: Journal of clinical and experimental hepatology (J Clin Exp Hepatol) 2023 Jul-Aug Vol. 13 Issue 4 Pg. 713-715 ISSN: 0973-6883 [Print] India
• PMID: 37440953 (Publication Type: Journal Article)
• Copyright: © 2023 Indian National Association for Study of the Liver. Published by Elsevier B.V. All rights reserved.