Abstract |
Interleukin-3 (IL-3) induces emergency hematopoiesis in settings of acute inflammation. In this issue of Immunity, Kiss et al. find that IL-3 derived from astrocytes and CD4+ T cells is a key regulatory cytokine of the central nervous system, and increased IL-3 signaling exacerbates neuroinflammation.
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Authors | Alice Bertocchi, Stephanie K Dougan |
Journal | Immunity
(Immunity)
Vol. 56
Issue 7
Pg. 1431-1433
(07 11 2023)
ISSN: 1097-4180 [Electronic] United States |
PMID | 37437533
(Publication Type: Journal Article, Comment)
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Copyright | Copyright © 2023 Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Interleukin-3
- Brain
- Central Nervous System
- Astrocytes
- Cytokines
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