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IL-3 finds its home in the brain.

Abstract
Interleukin-3 (IL-3) induces emergency hematopoiesis in settings of acute inflammation. In this issue of Immunity, Kiss et al. find that IL-3 derived from astrocytes and CD4+ T cells is a key regulatory cytokine of the central nervous system, and increased IL-3 signaling exacerbates neuroinflammation.
AuthorsAlice Bertocchi, Stephanie K Dougan
JournalImmunity (Immunity) Vol. 56 Issue 7 Pg. 1431-1433 (07 11 2023) ISSN: 1097-4180 [Electronic] United States
PMID37437533 (Publication Type: Journal Article, Comment)
CopyrightCopyright © 2023 Elsevier Inc. All rights reserved.
Chemical References
  • Interleukin-3
  • Cytokines
Topics
  • Interleukin-3
  • Brain
  • Central Nervous System
  • Astrocytes
  • Cytokines

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