The prevalence of coagulase-negative staphylococcus associated with bovine mastitis in China and its antimicrobial resistance rate: a meta-analysis.

Abstract

To contribute to the treatment decision and optimize coagulase-negative staphylococcus (CNS) control programs, we conducted a meta-analysis to investigate the epidemiology and antimicrobial resistance rates of coagulase-negative staphylococcus associated with bovine mastitis in China. Three databases (PubMed, Google scholar and China National Knowledge Infrastructure database) were utilized to obtain relevant publications. A total of 18 publications were included in our research, and 3 of them included antimicrobial resistant (AMR) test. The pooled prevalence of coagulase-negative staphylococcus was 17.28%. Subgroup analysis revealed that the prevalence was higher in South China than in North China, was higher in 2011-2020 than in 2000-2010 and was higher in clinical bovine mastitis cases than in subclinical cases. The pooled AMR were most resistant to β-lactams, followed by tetracyclines, quinolones, nitrofurans, lincosamides, sulfonamides, amphenicol and aminoglycosides. The pooled AMR rate of coagulase-negative staphylococcus was lower in 2011-2020 than in 2000-2010. Although the prevalence of CNS showed an increasing trend over 20 years, the AMR rate showed a decreasing trend, and the clinical type of mastitis was the most frequent and the prevalence was highest in South China. Finally, CNS was most resistant to β-lactams amongst the eight groups of antimicrobial agents.

• Authors: Jianming Deng, Kai Liu, Kuan Wang, Bowen Yang, Hui Xu, Juyu Wang, Feiyan Dai, Xiao Xiao, Xiaolong Gu, Limei Zhang, Weijie Qu
• Journal: The Journal of dairy research (J Dairy Res) Vol. 90 Issue 2 Pg. 158-163 (May 2023) ISSN: 1469-7629 [Electronic] England
• PMID: 37381099 (Publication Type: Meta-Analysis, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Coagulase
• beta-Lactams

Topics

• Cattle
• Female
• Animals
• Anti-Bacterial Agents (pharmacology)
• Coagulase
• Staphylococcal Infections (epidemiology, veterinary)
• Mastitis, Bovine (drug therapy, epidemiology)
• Prevalence
• Drug Resistance, Bacterial
• Staphylococcus
• beta-Lactams
• Microbial Sensitivity Tests (veterinary)
• Cattle Diseases