Effectiveness of photodynamic therapy adjunct to oral debridement in improving clinical, microbiological, and pain in necrotizing ulcerative gingivitis.

Abstract

To evaluate the efficacy of photodynamic therapy (PDT) as adjunctive to oral debridement (OD) in the improvement of clinical, microbiological, and pain in patients with necrotizing ulcerative gingivitis (NUG). Patients with NUG were split into two groups: Group-OD + PDT received PDT with OD, while Group-OD underwent OD alone. Clinical inflammatory parameters including full mouth plaque scores (FMPS), full mouth bleeding scores (FMBS), and probing depth (PD) were assessed. Fusobacterium nucleatum and Prevotella intermedia were analyzed using the polymerase chain reaction technique. Pain examination was done using various pain scales. Group PDT + OD showed more reduction in FMPS, FMBS, and greater reduction in F. nucleatum and P. intermedia count compared to group OD at 12 weeks follow up (p < 0.01). Group PDT + OD showed significantly lower pain scores at 12 weeks (p < 0.05). PDT was more effective in improving clinical parameters, and reducing bacterial counts and pain in NUG patients than dental scaling alone.

• Authors: Abdulaziz A Al-Kheraif, Ravish Javed, Mohammed Mahmoud Al-Momani, Aisha Wasi, Aftab Ahmed Khan
• Journal: Journal of biophotonics (J Biophotonics) Vol. 16 Issue 10 Pg. e202300197 (10 2023) ISSN: 1864-0648 [Electronic] Germany
• PMID: 37369626 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2023 Wiley-VCH GmbH.

Chemical References

• 2-(4-fluorophenyl)-N-methylsuccinimide

Topics

• Humans
• Photochemotherapy (methods)
• Debridement
• Fusobacterium nucleatum
• Gingivitis (drug therapy, microbiology)