Abstract |
Stentenbach and colleagues have unveiled a functional role of a human germline mutation found in the ribonuclease ( RNase) Z enzyme, ELAC2, in prostate cancer. Here, we discuss the importance of these findings in enhancing our understanding of how risk variants enable prostate cancer progression and the post-transcriptional mechanisms underlying oncogenesis.
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Authors | Steven Blinka, Rashmi Mishra, Andrew C Hsieh |
Journal | Trends in molecular medicine
(Trends Mol Med)
Vol. 29
Issue 8
Pg. 586-588
(Aug 2023)
ISSN: 1471-499X [Electronic] England |
PMID | 37353407
(Publication Type: Journal Article)
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Copyright | Copyright © 2023 Elsevier Ltd. All rights reserved. |
Chemical References |
- ELAC2 protein, human
- Neoplasm Proteins
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Topics |
- Male
- Humans
- Alleles
- Prostatic Neoplasms
(genetics)
- Genetic Predisposition to Disease
- Neoplasm Proteins
(genetics)
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