Abstract | INTRODUCTION:
Pityriasis lichenoides (PL) is a papulosquamous disease affecting both children and adults, for which narrowband-UVB (NB-UVB) phototherapy is regarded as a commonly used treatment option. The aim of this study was to investigate the efficacy of NB-UVB phototherapy in the management of PL and to compare response rates in pediatric and adult age groups. MATERIALS AND METHODS: RESULTS: A complete response (CR) was obtained in all pediatric patients with PL, while 53.8% of adult patients had achieved CR. The mean cumulative dose required to achieve the CR was higher in pediatric patients than adult patients with PL (p < .05). The CR was achieved in 6 (75%) of 8 PLEVA patients, while 8 (66.7%) of 12 PLC patients had reached to CR. The mean number of exposures for patients with PLC to achieve a CR was higher than patients with PLEVA (p < .05). Erythema was the most common adverse effect during phototherapy particularly in 5 (35.7%) of the patients with PL who had achieved CR. CONCLUSIONS: NB-UVB is an effective and well-tolerated treatment option for PL especially in diffuse types. A higher response can be obtained in children with higher cumulative dose. Patients with PLC may require more exposures for CR than patients with PLEVA.
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Authors | Esra Agaoglu, Hilal Kaya Erdogan, Ersoy Acer, Zeynep Nurhan Saracoglu, Muzaffer Bilgin |
Journal | Photodermatology, photoimmunology & photomedicine
(Photodermatol Photoimmunol Photomed)
Vol. 39
Issue 5
Pg. 520-526
(Sep 2023)
ISSN: 1600-0781 [Electronic] England |
PMID | 37340660
(Publication Type: Observational Study, Journal Article)
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Copyright | © 2023 The Authors. Photodermatology, Photoimmunology & Photomedicine published by John Wiley & Sons Ltd. |
Topics |
- Adult
- Humans
- Child
- Pityriasis Lichenoides
(radiotherapy)
- Retrospective Studies
- Ultraviolet Therapy
(adverse effects)
- Phototherapy
- Ultraviolet Rays
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