Background and Objectives: Phytotherapeutically, various herbal remedies, such as St. John's wort oil, have been introduced as
wound care options. Recently,
Neem oil has been considered a herbal option for the management of superficial
wounds.
Wound care is a complex process that involves several factors including the patient, caregiver, and medications. Herbal combinations could be an alternative to the chemical counterparts in the
wound care area. This report includes an investigation of the possible supportive impacts of the St. John's wort and
Neem oil containing
ointment (W Cura G Plus ®) in the management of
pressure ulcers (
PUs) in three intensive care unit (ICU) patients. Materials and Methods: The
ointment was administered to individuals once daily for 42 consecutive days. The status of individuals was macroscopically monitored by measuring the PU area and histopathological assessment of the tissue sections taken on the first and last days of
wound treatment. Results: The outcomes of the macroscopic and histopathological techniques exhibited that St. John's wort and
Neem oil containing
ointment provided a remarkable supportive impact on the patients that suffered from
PUs in the ICUs. Conclusions: The combination of St. John's wort and
Neem oil could be suggested as an efficient active phytoconstituent for the management of
PUs. The herbal
ointments may be suggested as an alternative for the patients that have
PUs in the ICUs.