Linear IgA bullous dermatosis in an acute myeloid leukemia patient: a rare case report.

Abstract

Linear IgA bullous dermatosis (LABD) is a rare autoimmune bullous disease characterized by linear IgA deposition along the skin basal membrane. In children, LABD classically presents with a "cluster of jewels" appearance, whereas in adults the classic presentation is itchy papules with tense vesicles and bullae on an erythematous base. We report the case of a 41-year-old woman with LABD that we suspect was induced by acute myeloid leukemia presenting with multiple vesicles and bullae that coalesced, forming the typical clinical manifestation of LABD and confirmed with histopathological and direct immunofluorescence. The patient was treated with a combination of oral and topical corticosteroids with excellent results.

• Authors: Deisy Vania Kianindra, Amelia Rosa, Dina Pebriany, Wiwiek Dewiyanti, Asnawi Madjid
• Journal: Acta dermatovenerologica Alpina, Pannonica, et Adriatica (Acta Dermatovenerol Alp Pannonica Adriat) Vol. 32 Issue 1 Pg. 19-22 (Mar 2023) ISSN: 1581-2979 [Electronic] Slovenia
• PMID: 36945763 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids

Topics

• Child
• Female
• Humans
• Adult
• Linear IgA Bullous Dermatosis (complications, drug therapy, chemically induced)
• Blister
• Glucocorticoids (therapeutic use)