En-face widefield optical coherence tomography angiography for understanding vascular networks changes in two cases of acute retinal necrosis.

Abstract

PURPOSE:

The present study assesses the utility of en-face widefield optical coherence tomography angiography (OCTA) imaging for evaluating the retinal vascular network during the course of treatment in acute retinal necrosis(ARN).

OBSERVATIONS:

OCTA images of two cases of acute retinal necrosis were analyzed. Case 1 was a 15-year-old male with visual crowding in his right eye who had best-corrected visual acuity of 16/20 and intraocular pressure of 25 mmHg in his right eye on initial evaluation. Case 2 was a 57-year-old male with visual crowding in his left eye who had best-corrected visual acuity of 20/20 in his left eye on initial examination and intraocular pressure of 19.3 mmHg. In both patients, dynamic changes could be tracked by en-face ultra-widefield OCTA imaging before and up to 1 year after surgical treatment. The images showed arteriovenous anastomosis and the nonperfused area on the surface of the retina.

CONCLUSIONS AND IMPORTANCE:

En-face widefield OCTA is useful for monitoring the structure of retinal vessels over time in acute retinal necrosis. Wide-angle OCTA is used to non-invasively examine retinal vascular dynamic changes in ARN. OCTA artifacts due to intraocular inflammation appeared, making interpretation difficult. These will remain as issues in the future. It seems difficult for a while to completely replace FA due to the problem of image clarity.

• Authors: Mami Tomita, Mizuki Tagami, Norihiko Misawa, Atsushi Sakai, Yusuke Haruna, Shigeru Honda
• Journal: Journal of ophthalmic inflammation and infection (J Ophthalmic Inflamm Infect) Vol. 13 Issue 1 Pg. 9 (Mar 07 2023) ISSN: 1869-5760 [Print] Germany
• PMID: 36881194 (Publication Type: Journal Article)
• Copyright: © 2023. The Author(s).