Gene expression data visualization tool on the o²S²PARC platform.

Abstract

Background: The identification of differentially expressed genes and their associated biological processes, molecular function, and cellular components are important for genetic diseases studies because they present potential biomarkers and therapeutic targets. Methods: In this study, we developed an o²S²PARC template representing an interactive pipeline for the gene expression data visualization and ontologies data analysis and visualization.  To demonstrate the usefulness of the tool, we performed a case study on a publicly available dataset. Results: The tool enables users to identify the differentially expressed genes (DEGs) and visualize them in a volcano plot format. The ontologies associated with the DEGs are determined and visualized in barplots. Conclusions: The "Expression data visualization" template is publicly available on the o²S²PARC platform.

• Authors: Hiba Ben Aribi, Mengyuan Ding, Anmol Kiran
• Journal: F1000Research (F1000Res) Vol. 11 Pg. 1267 ( 2022) ISSN: 2046-1402 [Electronic] England
• PMID: 36816807 (Publication Type: Journal Article)
• Copyright: Copyright: © 2022 Ben Aribi H et al.