Cobalamin is an essential molecule for humans; it is exceptionally important for various body functions, including
deoxyribonucleic acid synthesis and cellular energy production. Vegans are more vulnerable to
vitamin B12 deficiency than natives with moderate consumption of animal dietary supplements or people with inadequate nutritional patterns. However, the long-term effects of sub-medical deficiency have not been thoroughly studied, but they may have a negative impact on the cardiovascular system, pregnancy outcomes, and vascular, renal, cognitive, bone, and eye health. Alongside the
statin remedy, that is a powerful approach for CVD prevention. Another approach is related to the B nutrition substitution remedy with
folic acid, and
vitamins B6 and B12 are extensively practised nowadays. There is a tremendous interest in plasma
homocysteine (tHcy) as a cardiovascular hazard factor. However, current research in the field of its prevention is more inclined toward confirming the benefit of tHcy-reducing remedy with
vitamin B12. Thus, while
folic acid fortification is primarily aimed at reducing
neural-tube defects, it may also play a significant role in the primary prevention of CVD by lowering tHcy.
Folate and
B-vitamins play important roles in CVD prevention and nutrition policy implementation. Patients affected with
Chronic Kidney Disease (CKD) or end-stage Stage Renal Disease (
ESRD) experience a tremendous cardiovascular threat that may also further lead to death. As a result, routine monitoring of
vitamin B12 levels is likely to be beneficial for the early detection and treatment of metabolic
vitamin B12 deficiency, as well as the prevention of heart-related diseases.