Brain Nocardiosis Defined by 18 F-Fluorocholine PET/CT.

Abstract

ABSTRACT:

Nocardia infection (nocardiosis) is usually acquired by inhalation; so pulmonary nocardiosis is the most common clinical presentation. Extrapulmonary localization occurs through hematogenous dissemination or contiguous spread. Nocardia can involve the central nervous system in a very reduced number of patients, mainly in immunocompromised. We present a case of a 56-year-old woman with a history of aggressive systemic mastocytosis, treated with chemotherapy 1 year ago. Patient reported intense headache, disorientation, and blurry vision without other symptoms being diagnosed with a rare brain nocardiosis by Nocardia cerradoensis . Neither bacteremia nor pulmonary involvement was detected. Brain PET/CT illustrated 18 F-fluorocholine avidity on brain abscesses.

• Authors: Ana María García Vicente, Edel Noriega Álvarez, Jose Carlos González Rodríguez, Ángel María Soriano Castrejón
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 48 Issue 4 Pg. 327-329 (Apr 01 2023) ISSN: 1536-0229 [Electronic] United States
• PMID: 36727854 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Chemical References

• fluorocholine

Topics

• Female
• Humans
• Middle Aged
• Positron Emission Tomography Computed Tomography
• Nocardia Infections
• Brain Abscess
• Brain