Role of small intestinal submucosa extracellular matrix in advanced regenerative wound therapy.

Abstract

Advanced regenerative therapies using cellular and tissue-based products (CTPs) can play an important role in effective management of hard-to-heal wounds. CTPs derived from allogenic or xenogenic tissues use an extracellular matrix (ECM) to provide a therapeutic ECM scaffold in the wound bed to facilitate tissue regeneration. One such example is OASIS Extracellular Matrix (Cook Biotech Incorporated), a porcine small intestinal submucosa extracellular matrix (SIS-ECM) that preclinical and clinical data have shown to be tolerable and effective in promoting tissue regeneration in hard-to-heal wounds.

• Authors: Richard Simman
• Journal: Journal of wound care (J Wound Care) Vol. 32 Issue Sup2 Pg. S3-S10 (Jan 01 2023) ISSN: 0969-0700 [Print] England
• PMID: 36724085 (Publication Type: Journal Article)

Topics

• Animals
• Swine
• Tissue Scaffolds
• Intestine, Small
• Extracellular Matrix
• Wound Healing
• Cell Proliferation