General anaesthesia for photodynamic therapy of port-wine stain in children: A retrospective study.

Abstract

AIMS:

This report intended to assess the safety and efficiency of general anaesthesia with preserved spontaneous breathing for pain management in photodynamic therapy (PDT) of port-wine stains (PWS) in paediatric patients.

METHODS:

This study included 1960 Hemoporfin PDT procedures performed under general anaesthesia on 560 PWS patients. Medical records were retrospectively analysed. All of the procedures performed under general anaesthesia with preserved spontaneous breathing.

RESULTS:

The patients comprised males (43.93%) and females (56.07%). Ninety percent of cases were ASA class I, and 10% were class II, no case was class III or higher. Adverse events accompanying general anaesthesia included postoperative irritability (8.98%), carbon dioxide pressure (PCO2) >50 mmHg (15.97%), movement during surgery (6.98%), vomiting (0.2%), laryngospasm (0.2%), unplanned endotracheal intubation (0.05%), upper airway obstruction (0.05%), and hypoxia (0.1%). The FLACC score was <4 points in 84% of cases and 4∼6 points in 16% of cases.

CONCLUSIONS:

General anaesthesia with preserved spontaneous breathing has few complications and appears safe and feasible for PDT in most children with PWS.

• Authors: Linlin Tang, Wei Liu, Qian Yu, Hongjie Guo, Xue Yang, Ling Xiong
• Journal: Photodiagnosis and photodynamic therapy (Photodiagnosis Photodyn Ther) Vol. 41 Pg. 103273 (Mar 2023) ISSN: 1873-1597 [Electronic] Netherlands
• PMID: 36627066 (Publication Type: Journal Article)
• Copyright: Copyright © 2023 Elsevier B.V. All rights reserved.

Chemical References

• Photosensitizing Agents

Topics

• Male
• Female
• Humans
• Child
• Port-Wine Stain (drug therapy)
• Retrospective Studies
• Photosensitizing Agents (therapeutic use)
• Photochemotherapy (methods)
• Anesthesia, General