Efficacy and safety of external therapy of TCM for diabetic peripheral vascular disease: A protocol for systematic review and meta-analysis.

Abstract

BACKGROUND:

In modern society, the incidence of diabetes is increasing yearly, and poor glycemic control can accelerate the progression and severity of diabetic peripheral vascular disease. External treatment with traditional Chinese medicine (TCM) has been widely used in the treatment of diabetes, but there is no systematic review on the external treatment of TCM for diabetic peripheral vascular disease; therefore, this study aimed to conduct a meta-analysis on the clinical efficacy and safety of external treatment of TCM in the treatment of diabetic peripheral vascular diseases.

METHODS:

We searched The Cochrane Library, PubMed, Web of Science, EMBASE, China Science and Technology Journal, China National Knowledge Infrastructure, Wanfang, Chinese Biomedical Literature Database, and other sources from their respective inception dates to October 20, 2022, to identify potentially eligible studies. We will use Review Manager 5.4 software provided by the Cochrane Collaborative Network for statistical analysis. We then assessed the quality and risk of the included studies and observed their outcome measures.

RESULTS:

Changes in the bilateral femoral artery, popliteal artery, dorsal artery diameter, blood flow, ankle/brachial index, and dorsal foot temperature: An overall reduction in symptoms (a reduction in diabetes-related symptoms that occur only during the intervention or as a result of the intervention, including peripheral vascular disease).

CONCLUSION:

The objective of this meta-analysis was to investigate the influence of external treatment of traditional Chinese medicine on diabetic peripheral vascular disease and to provide more methods for the clinical prevention and treatment of diabetic peripheral vascular disease.

• Authors: Tingwei Ding, Lei Sheng, Haiyu Zhu, Hongyi Guan, Ying Wang, Haoze Guo, Yunpeng Bi, Bailin Song
• Journal: Medicine (Medicine (Baltimore)) Vol. 101 Issue 51 Pg. e32362 (Dec 23 2022) ISSN: 1536-5964 [Electronic] United States
• PMID: 36595808 (Publication Type: Journal Article)
• Copyright: Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

Chemical References

• Drugs, Chinese Herbal

Topics

• Humans
• Medicine, Chinese Traditional (methods)
• Drugs, Chinese Herbal (therapeutic use)
• Systematic Reviews as Topic
• Meta-Analysis as Topic
• Diabetic Neuropathies (drug therapy)
• Diabetic Angiopathies (drug therapy)
• Peripheral Vascular Diseases
• Diabetes Mellitus (drug therapy)