Additional Steroid Therapy for Delayed Facial Palsy in Miller Fisher Syndrome.

Abstract

Miller Fisher syndrome (MFS) is a variant of Guillain-Barré syndrome. Delayed facial palsy (DFP) is a symptom that occurs after other neurological symptoms begin to recover within four weeks from the onset of MFS. As there have been few detailed reports about DFP in MFS cases treated with additional immunotherapy, we investigated three cases of DFP in MFS treated with additional steroid therapies. The duration of facial palsy in our cases was 12-24 days. No severe adverse effects were observed. Although adverse side effects should be carefully monitored, additional steroid therapy might be a treatment option for MFS-DFP.

• Authors: Shohei Watanabe, Yusuke Tokuhara, Mari Hiratsuka, Kazuki Yoshizumi, Shinichiro Ukon, Shuhei Kasama, Masanaka Takeda, Kei Funakoshi, Takashi Kimura
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 61 Issue 22 Pg. 3435-3438 ( 2022) ISSN: 1349-7235 [Electronic] Japan
• PMID: 36385049 (Publication Type: Journal Article)

Chemical References

• Steroids

Topics

• Humans
• Drug-Related Side Effects and Adverse Reactions
• Facial Paralysis (drug therapy, etiology)
• Guillain-Barre Syndrome (diagnosis)
• Miller Fisher Syndrome (complications, drug therapy, diagnosis)
• Steroids (therapeutic use)